Alakesh Bisai

Organic and Organometallic Chemistry

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Academic Details

Associate Professor: Department of Chemistry, IISER Bhopal (Nov. 2013 - till date)

Assistant Professor: Department of Chemistry, IISER Bhopal (Dec. 2009 - Nov. 2013)

Post-Doc.: Department of Chemistry, UC Berkeley (Oct. 2006- Dec. 2009). Research Advisor: Prof. Richmond Sarpong

Ph.D.: Department of Chemistry, IIT Kanpur (Sept. 2006). Thesis Advisor: Prof. Vinod K. Singh

Profile Details

    The design, discovery and the development of efficient small molecule catalysts for enantioselective C-C and C-hetero bond-forming reactions and their application.!

    Total syntheses of architecturally interesting biologically active natural products which provide an ideal platform for the invention of highly selective organic transformations.

    Research Interests

Authors Title of Article Journal Year
Saikat Chaudhuri
Santanu Ghosh
Subhajit Bhunia
Alakesh Bisai
Catalytic Asymmetric Formal Total Syntheses of (+)- and (-)-Cycloclavine
Details
Chemical Communications 2018
Avishek Roy
Mrinal K Das
Saikat Chaudhuri
Alakesh Bisai
Transition-Metal Free Oxidative Alkynylation of 2-Oxindoles with Ethynylbenziodoxolone (EBX) Reagents
Details
J. Org. Chem. 2018
Saikat Chaudhuri
Subhajit Bhunia
Avishek Roy
Mrinal K Das
Alakesh Bisai
Biomimetic Total Syntheses of Clavine Alkaloids
Details
Organic Letters 2018
Nivesh Kumar
Vipin R Gavit
Manvendra Singh
Alakesh Bisai
Synthesis of 3-hydroxy 2-oxindoles via deacylative oxygenation (DaO) : Total synthesis of CPC-1
Details
J. Indian Chem. Soc. 2017
Lakshmana K Kinthada
Raghavendra Sai Medisetty
Amarchand Parida
Naresh Babu K
Alakesh Bisai
FeCl3-Catalyzed Allylation Reactions onto 3-Hydroxy-2-oxindoles: Formal Total Syntheses of Bis-cyclotryptamine Alkaloids, Chimonanthine, and Folicanthine
Details
J. Org. Chem. 2017
Alakesh Bisai
Saikat Chaudhuri
Subhajit Bhunia
Total Syntheses of Pyroclavine, Festuclavine, Lysergol, and Isolysergol via a Catalytic Asymmetric Nitro-Michael Reaction*
Details
Chemistry - A European Journal 2017
Lakshmana K. Kinthada
K. Naresh Babu
Dikshaa Padhi
Alakesh Bisai
Lewis-Acid-Catalysed Reaction of 3-Hydroxy-2-oxindoles with Terminal Alkynes: Synthetic Approaches to the Pyrroloindoline Alkaloids
Details
Eur. J. Org. Chem. 2017
Nivesh Kumar
Mrinal Kanti Das
Santanu Ghosh
Alakesh Bisai
Development of catalytic deacylative alkylations (DaA) of 3-acyl-2-oxindoles: total synthesis of meso-chimonanthine and related alkaloids
Details
Chemical Communications 2017
Adiki Raja Sekhar
Santhosh K. Sariki
R. V. Ramana Reddy
Alakesh Bisai
Puspendra K. Sahu
Raghuvir S. Tomar
Jeyaraman Sankar
Zwitterionic BODIPYs with Larger Stokes Shift: Small Molecular Biomarkers for Live Cells
Details
Chemical Communications 2017
Subhadip N. De
Mrinal Kanti Das
Avishek Roy
Ala Bisai
Synthesis of 2 Oxindoles Sharing Vicinal All-Carbon Quaternary Stereocenters via Organocatalytic Aldol Reaction
Details
The Journal of Organic Chemistry 2016
Badrinath N. Kakde
Amarchand Parida
Nivesh Kumar
Abhishek Mourya
Alakesh Bisai
FeCl3-Catalyzed Highly Efficient Nazarov Type Cyclization of Arylvinylcarbinols: Total Synthesis of ()-Dichroanal B and Related Taiwaniaquinoids
Details
ChemistrySelect 2016
Pooja Kumari
Amarchand Parida
Badrinath N. Kakde
Alakesh Bisai
Total Syntheses of Taiwaniaquinol D and Taiwaniaquinone D via a key Lewis Acid-Catalyzed Nazarov Type Cyclization
Details
Tetrahedron Letters 2016
Nivesh Kumar
Santanu Ghosh
Subhajit Bhunia
Alakesh Bisai
Synthesis of 2-oxindoles via 'transition-metal-free' intramolecular dehydrogenative coupling (IDC) of sp2 C-H and sp3 C-H bonds
Details
Beilstein J. Org. Chem. 2016
Badrinath N. Kakde
Nivesh Kumar
Pradip Kumar Mondal
Alakesh Bisai
Approach to Merosesquiterpenes via Lewis Acid Catalyzed Nazarov Type Cyclization: Total Synthesis of Akaol A
Details
Organic Letters 2016
Mrinal Kanti Das
Subhadip De
Shubhashish
Alakesh Bisai
Concise Total Syntheses of Joubertiamine, O-Methyl-joubertiamine, 3'-Methoxy-4'-O-methyljoubertiamine, Mesembrane, and Crinane
Details
Synthesis 2016
Saikat Chaudhuri
Amarchand Parida
Santanu Ghosh
Alakesh Bisai
Highly Stereoselective Syntheses of Proline Derived Vicinal Amino Alcohols via Grignard Addition onto N-Tosylprolinal
Details
Synlett 2016
Subhadip De
Mrinal Kanti Das
Subhajit Bhunia
Alakesh Bisai
Unified Approach to the Spiro(pyrrolidinyl-oxindole) and Hexahydropyrrolo[2,3-b]indole Alkaloids: Total Syntheses of Pseudophrynamines 270 and 272A
Details
Organic Letters 2015
Santanu Ghosh
Saikat Chaudhuri
Alakesh Bisai
Catalytic Enantioselective Decarboxylative Allylations of a Mixture of Allylcarbonates and Allylesters: Total Syntheses of (-)- and (+)-Folicanthine
Details
Chemistry - A European Journal 2015
Badrinath N. Kakde
Pooja Kumari
Alakesh Bisai
Total Synthesis of (±)-Taiwaniaquinol F and Related Taiwaniaquinoids
Details
The Journal of Organic Chemistry 2015
Santanu Ghosh
Lakshmana K. Kinthada
K. Naresh Babu
Alakesh Bisai
Highly chemoselective synthesis of dimeric 2-oxindoles with a C-3/C-5′ linkage via Friedel–Crafts alkylations of 2-oxindoles with 3-hydroxy-2-oxindoles
Details
Organic & Biomolecular Chemistry 2015
Amarchand Parida
Sharique Mohd.
Badrinath N. Kakde
Santanu Ghosh
Alakesh Bisai
Efficient Synthesis of 3-Alkynyl-2-(hydroxymethyl)cyclohex-2-en-1-ones by a Stork–Danheiser Sequence from Vinylogous Esters and Terminal Alkynes
Details
Synthesis 2015
Alakesh Bisai
Saikat Chaudhuri
Santanu Ghosh
Oxidative Dimerization of 2‑Oxindoles Promoted by KOt Bu‑I2: Total Synthesis of (±)-Folicanthine
Details
Organic Letters 2015
Mrinal Kanti Das
Subhadip De
Shubhashish
Alakesh Bisai
Concise total syntheses of (±)-mesembrane and (±)-crinane
Details
Organic & Biomolecular Chemistry 2015
Sharique Mohd.
K. Naresh Babu
Santanu Ghosh
Lakshmana K. Kinthada
Soumava Biswas
Alakesh Bisai
Friedel–Crafts alkylations of electron-rich aromatics with 3-hydroxy-2-oxindoles: scope and limitations
Details
Organic & Biomolecular Chemistry 2014
Santanu Ghosh
Subhajit Bhunia
Badrinath N. Kakde
Subhadip De
Alakesh Bisai
Enantioselective Construction of Vicinal All-Carbon Quaternary Centers via Catalytic Double Asymmetric Decarboxylative Allylation
Details
Chemical Communications 2014
Subhajit Bhunia
Subhadip De
Santanu Ghosh
Lakshmana K. Kinthada
Dhananjay Dey
Alakesh Bisai
Acid-catalyzed reactions of 3-hydroxy-2-oxindoles with electron-rich substrates: synthesis of 2-oxindoles with all-carbon quaternary center
Details
Organic & Biomolecular Chemistry 2013
Subhadip De
Saikat Chaudhuri
Sourabh Mishra
Himanshu Mamtani
Alakesh Bisai
Pd-Catalyzed Direct Arylation Approach to the 6H-dibenzo[c,h]chromenes: Total Synthesis of Arnottin I
Details
J. Ind. Chem. Soc. 2013
Subhadip De
Sourabh Mishra
Badrinath N. Kakde
Dhananjay Dey
Alakesh Bisai
Expeditious Approach to Pyrrolophenanthridones, Phenanthridines, and Benzo[c]phenanthridines via Organocatalytic Direct Biaryl-Coupling Promoted by Potassium tert-Butoxide
Details
The Journal of Organic Chemistry 2013
Sourabh Mishra
Subhadip De
Badrinath N. Kakde
Alakesh Bisai
Expeditious Approach to the Amarylidaceae Alkaloids via a Pd-Catalyzed Direct Biaryl-Coupling Reactions
Details
Indian Journal of Chemistry-A 2013
Subhajit Bhunia
Santanu Ghosh
Dhananjay Dey
Alakesh Bisai
DDQ-mediated Direct IntramolecularDehydrogenative-Coupling (IDC): Expeditious Approach to the Tetracyclic Core of Ergot Alkaloids
Details
Organic Letters 2013
Badrinath N. Kakde
Subhadip De
Dhananjay Dey
Alakesh Bisai
Metal triflate-catalyzed cyclization of arylvinylcarbinols: formal synthesis of (±)-dichroanone and (±)-taiwaniaquinone H
Details
RSC Advances 2013
Badrinath N. Kakde
Subhajit Bhunia
Alakesh Bisai
Approach to the core structure of abeo-abietanes and gibberellins via Stork–Danheiser sequence followed by Friedel–Crafts alkylations
Details
Tetrahedron Letters 2013
Santanu Ghosh
Subhadip De
Badrinath N. Kakde
Subhajit Bhunia
Amit Adhikary
Alakesh Bisai
Intramolecular Dehydrogenative Coupling of sp2 C–H and sp3 C–H Bonds: An Expeditious Route to 2-Oxindoles
Details
Organic Letters 2012
Subhadip De
Lakshmana K. Kinthada
Alakesh Bisai
Base-Promoted Michael Reaction Concomitant with Alkylation of Cyclic-1,3- diones, an Efficient Approach to 2-Substituted Vinylogous Ester
Details
Synlett 2012
Santanu Ghosh
Lakshmana K. Kinthada
Subhajit Bhunia
Alakesh Bisai
Lewis acid-catalyzed Friedel–Crafts alkylations of 3-hydroxy-2-oxindole: an efficient approach to the core structure of azonazine
Details
Chemical Communications 2012
Subhadip De
Santanu Ghosh
Subhajit Bhunia
Javeed Ahmad Sheikh
Alakesh Bisai
Intramolecular Direct Dehydrohalide Coupling Promoted by KOtBu: Total Synthesis of Amaryllidaceae Alkaloids Anhydrolycorinone and Oxoassoanine
Details
Organic Letters 2012
Vishnumaya Bisai
Alakesh Bisai
Vinod K. Singh
Enantioselective Organocatalytic Aldol Reaction Using Small Organic Molecules
Details
Tetrahedron 2012