Dr. Manmohan Kapur

Organic Chemistry

  • Designation : Associate Professor
  • Phone : +91 755 269 1331, 669 1331
  • Email : mk@iiserb.ac.in
  • Fax : +91 755 669 2392
Academic Details

Associate Professor (June 2015 -), Chemistry, Indian Institute of Science Education and Research Bhopal

Assistant Professor (July 2009-May 2015),Chemistry, Indian Institute of Science Education and Research, Bhopal, India.

Group Leader (Jan 2007- July 2009), Jubilant Chemsys Ltd., Noida, INDIA.

Senior Research Scientist (April 2006 - Jan 2007), Chembiotek Research International Pvt Ltd., Pune, INDIA.

Post-Doctoral (Oct 2004 - March 2006), Research Associate (AvH Post Doc Fellow) Institut für Organische Chemie, Universität Tübingen, GERMANY. Advisor: Prof. Dr. Martin E. Maier.

Post-Doctoral (July 2003 - June 2004), Research Associate Department of Chemistry, Wayne State University, Detroit, USA. Advisor: Prof. Jin K. Cha.

Ph. D. (July 1997 - Dec 2002), in Chemistry (National Chemical Laboratory, Pune, INDIA). Advisor: Dr. Ganesh Pandey.

Profile Details

    Enantioselective synthesis of substituted heterocyclic natural products using C-H functionalization as the key step.

    Transition metal catalysis

    • One substrate, two modes of C-H Functionalization: A Metal-Controlled Site-selectivity Switch in C-H arylation reactions. Tiwari, V. K.; Kamal, N.; Kapur, M. Org. Lett. 2017, 19, 0000-0000 (Just accepted).

    • Product Control using Substrate Design: Ruthenium-catalyzed Oxidative C-H Olefinations of Cyclic Weinreb Amides. Das, R.; Kapur, M. Chem. -Eur. J. 2016, 22, 16986-16990.

    • Ruthenium-catalyzed, Site-selective C-H Allylation of Indoles with Allyl Alcohols as Coupling Partners. Kumar, G. S.; Kapur, M. Org. Lett. 2016, 18, 1112-1115.

    • Palladium (II)-catalyzed Heteroatom-directed Regioselective C-H Nitration of Anilines using Pyrimidine as a Removable Directing Group. Pawar, G. G.; Brahmanandan, A.; Kapur, M. Org. Lett. 2016, 18, 448-451.

    • Palladium-catalyzed Synthesis of 2-Alkenyl-3-Arylindoles via Dual alpha-Arylation Strategy: Formal Synthesis of the Antilipemic Drug Fluvastatin. Kale, A. P.; Kumar, G. S.; Kapur, M. Org. Biomol. Chem. 2015, 13, 10995-11002.

    • Fujiwara-Moritani Reaction of Weinreb Amides using a Ruthenium-catalyzed C-H Functionalization Reaction. Das, R.; Kapur, M. Chem. -Asian. J. 2015, 10, 1505-1512.

    • Heteroatom-guided Palladium-catalyzed Site-selective C-H Arylation of 4H-Chromenes: Diastereoselective Assembly of the Core Structure of Myristinin B via Dual C-H Functionalization. Pawar, G. G.; Tiwari, V. K.; Jena, H. K.; Kapur, M. Chem. -Eur. J. 2015, 21, 9905-9911.

    • Palladium-Catalyzed alpha-Arylation of Enones in the Synthesis of 2-Alkenyl Indoles and Carbazoles. Kale, A. P.; Kumar, G. S.; Arun Raj, K. M.; Kapur, M. Org. Lett. 2015, 17, 1324-1327.

    • Ruthenium-catalyzed Heteroatom-directed Regioselective C-H Arylation of Indoles using a Removable Tether.Tiwari, V. K.; Kamal, N.; Kapur, M. Org. Lett. 2015, 17, 1766-1769.

    • Temperature Induced Morphological Transitions from Native to Unfolded Aggregated States of Human Serum Albumin. Das, N.; Ghosh, N; Kale, A. P.; Mondal, R.; Anand, U.; Ghosh, S.; Tiwari, V. K.; Kapur, M.; Mukherjee, S. J. Phys. Chem. (B) 2014, 118, 7267-7276.

    • Palladium catalyzed, heteroatom-guided C-H functionalization in the synthesis of substituted isoquinolines and dihydroisoquinolines. Tiwari, V. K.; Pawar, G. G.; Jena, H. K.; Kapur, M. Chem. Commun. 2014, 50, 7322-7325.

    • Heteroatom-Guided, Palladium-Catalyzed Regioselective C–H Functionalization in the Synthesis of 3-Arylquinolines. Tiwari, V. K.; Pawar, G. G.; Das, R.; Adhikary A.; Kapur, M. Org. Lett. 2013, 15, 3310-3313.

    • Dehydrogenative Heck Reaction (Fujiwara-Moritani Reaction) of Unactivated Olefins with simple Dihydropyrans under Aprotic Conditions. Pawar, G. G.; Singh, G.; Tiwari, V. K.; Kapur, M. Adv. Synth. Catal. 2013, 355, 2185-2190.

    • Regioselectivity Switch Achieved in the Palladium Catalyzed a-Arylation of Enones by Employing the Modified Kuwajima-Urabe Conditions. Kale, A. P.; Pawar, G. G.; Kapur, M.; Org. Lett. 2012, 14, 1808-1811.