Ishu Saraogi

Organic Chemistry and Chemical Biology

  • Designation : Associate Professor
  • Phone : +91 755 269 1309
  • Email : ishu@iiserb.ac.in

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Academic Details

Assistant Professor,Chemistry, Indian Institute of Science Education and Research, Bhopal, India.

Post-Doctoral California Institute of Technology, USA. Advisor: Shu-ou Shan

Ph. D. (2008),Yale University, USA. Advisor: Andrew D. Hamilton

M.S. (2003),Indian Institute of Science, Bangalore. Advisor: T. N. Guru Row

B.Sc.(Honors) (2000),University of Calcutta.

Profile Details

    Using a combination of organic chemistry and molecular biology techniques, our research will be focused in the following areas:

    Exploiting protein biosynthesis machinery for non-natural applications using stop codon reassignment.

    Biophysical and biochemical assays for studying protein-protein and protein-ligand binding with a strong emphasis on fluorescence.

    High-throughput and rational design methods to inhibit protein-protein interactions, primarily aimed at identifying novel antibacterial targets.

Authors Title of Article Journal Year
Upasana Potteth
Tulsi Upadhyay
Vaibhav Karekar
Ishu Saraogi
A stutter in the coiled-coil domain of E.coli co-chaperone GrpE connects structure with function
Details
Biochemistry 2021
Upasana S Potteth
Tulsi Upadhyay
Snehlata Saini
Ishu Saraogi
Novel Antibacterial Targets in Protein Biogenesis Pathways
Details
ChemBioChem 2021
Jainu Ajit
Anirban Das
Yogesh Gangarde
Ishu Saraogi
Synthesis and Evaluation of Arylamides with Hydrophobic Side Chains for Insulin Aggregation Inhibition
Details
ChemPlusChem 2021
Anirban Das
Tanoy Datta
Laxmikant Gadhe
Apurba Lal Koner
Ishu Saraogi
Biocompatible fluorescent probe for selective detection of amyloid fibrils
Details
Analytical Chemistry 2020
Anirban Das
Yogesh Gangarde
Viniti Tomar
Omkar Shinde
Tulsi Upadhyay
Sarfaraz Alam
Sudipta Ghosh
Varun Chaudhary
Ishu Saraogi
A small molecule inhibitor prevents insulin fibrillogenesis and preserves activity
Details
Molecular Pharmaceutics 2020
Yogesh Gangarde
Sajeev T K
Nihar Panigrahi
Ram K Mishra
Ishu Saraogi
Amphiphilic small molecule assemblies to enhance the solubility and stability of hydrophobic drugs
Details
ACS Omega 2020
Bapurao Bhoge
Purnima Mala
Jo S Kurian
Varadharajan Srinivasan
Ishu Saraogi
Selective functionalization at N2-position of guanine in oligonucleotides via reductive amination
Details
Chemical Communications 2020
Vaibhav Karekar
Bhoge Bapurao
Saraogi Ishu
An expeditious synthetic route to proteomimetic foldamers
Details
New Journal of Chemistry 2019
Ishu Saraogi
Snehlata Saini
Sudipta Ghosh
Peptide nucleic acid mediated inhibition of the bacterial signal recognition particle
Details
Chemical Communications 2018
Ishu Saraogi
David Akopian
Shu-ou Shan
Real time fluorescence reveals the recognition, commitment, and unloading of cargo during co-translational protein targeting
Details
Jl. Of Cell Biology 2014
Ishu Saraogi
Shu-ou Shan
Co-translational protein targeting to the bacterial membrane
Details
BBA-Molecular Cell Research 2014

Book Chapters

Author Editors Title Publisher Year
Ishu Saraogi
Bapurao A Bhoge
Yogesh M Gangarde
Jerry Atwood
Len Barbour
George Gokel
Supramolecular Assemblies in Chemical Biology Elsevier 2017